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KMID : 0385219930030020065
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Korean Journal of Gerontology
1993 Volume.3 No. 2 p.65 ~ p.67
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Effect of energy restriction on c-Ha-ras c-fos mRNA levels in female rats
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Baik Myung-Gi
Park Chung-Sun
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Abstract
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Our Previous study has shown that energy restriction reduces c-Ha-ras and c-fos mRNA levels in mammary tissues, but not the levels in the liver of female rats. In the present study, we further investigated whether 30% energy restriction from five weeks to 20 weeks affects c-Ha-ras and c-fos mRNA levels in various tissues including salivary gland, uterus, ovary, lung, and skin of female rats. Both c-Ha-ras and c-fos mRNA levels were highest in the skin. Energy restriction did not affect either c-Ha-ras or c-fos mRNA levels in any tissue examined. Results from our previous and present studies suggest that the effect of energy restriction on the expression of c-Ha-ras and c-fos mRNA is tissue-specific.
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KEYWORD
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female rats, energy restriction, c-Ha-ras, c-fos
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